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๐ฟ Curcumin (Turmeric)
Most studied natural compound for GBM with proven TMZ synergy
| Property | Detail |
|---|
| Source | Curcuma longa (turmeric) |
| Evidence | โ Human Study 2025 โ TMZ Synergy |
| Crosses BBB | Yes (liposomal or with piperine) |
Key Studies
2025 Clinical Study (72 patients)
Curcumin + Boswellia + Polydatin + standard treatment = improved survival
MDPI Cancers โ
Mechanisms
- Inhibits GBM cell proliferation
- Induces apoptosis
- Synergizes with TMZ
- Anti-inflammatory (NF-ฮบB)
- Anti-angiogenic
Dosage
| Form | Dose |
|---|
| Liposomal/Phytosome | 1000-2000 mg/day |
| With piperine | 1500-2000 mg/day |
Products
- Thorne Meriva-SF โ Phytosome form
- NOW Curcumin Phytosome
- LipoMicel Curcumin โ Liposomal
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